PDB | 8etm Human triacylglycerol synthesizing enzyme DGAT1
Human triacylglycerol synthesizing enzyme DGAT1 in complex with DGAT1IN1 inhibitor
label Keywords
triglyceride biosynthesis, lipid storage, lipid metabolism, membrane protein, transferase-transferase inhibitor complex
event_note Published
06/19/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
[(1S,4r)-4-{4-[(4S)-2-({[4-(trifluoromethoxy)phenyl]methyl}carbamoyl)imidazo[1,2-a]pyridin-6-yl]phenyl}cyclohexyl]acetic acid
Original publication
import_contacts Title
Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis.
import_contacts Journal
Nat Commun 2023
import_contacts DOI
10.1038/s41467-023-38934-3
person Authors
Wang, K., Lee, C.W., Walther, T.C., Farese Jr., R.V., Xu, C., Song, J., Song, K., Sui, X., Liao, M.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Wang, K., Lee, C.W., Walther, T.C., Farese Jr., R.V., Xu, C., Song, J., Song, K., Sui, X., Liao, M. , provided free of copyright via the Protein DataBank. View original data or read license terms.
