PDB | 8eog Structure of the human L-type voltage-gated calcium channel Cav1.2 complexed
Structure of the human L-type voltage-gated calcium channel Cav1.2 complexed with L-leucine
label Keywords
voltage-gated calcium channel, cav alpha2delta, drug binding, gabapentinoid, membrane protein
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, SODIUM ION, LEUCINE, CHOLESTEROL, (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl dodecanoate, (2R)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(dodecanoyloxy)propyl heptadecanoate
Original publication
import_contacts Title
EMC chaperone-Ca V structure reveals an ion channel assembly intermediate.
import_contacts Journal
Nature 2023
import_contacts DOI
10.1038/s41586-023-06175-5
person Authors
Chen, Z., Niranjan, S., Abderemane-Ali, F., Montano, J.L., Jang, S., Mondal, A., Zaro, B.W., Minor Jr., D.L.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Chen, Z., Niranjan, S., Abderemane-Ali, F., Montano, J.L., Jang, S., Mondal, A., Zaro, B.W., Minor Jr., D.L. , provided free of copyright via the Protein DataBank. View original data or read license terms.
