PDB | 8ea0 MiniGq-coupled hM3R
CryoEM structure of miniGq-coupled hM3R in complex with iperoxo (local refinement)
label Keywords
gpcr, ixo, active state, membrane protein, hm3r, iperoxo
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium, CHOLESTEROL HEMISUCCINATE
Original publication
import_contacts Title
Molecular basis for selective activation of DREADD-based chemogenetics.
import_contacts Journal
Nature 2022
import_contacts DOI
10.1038/s41586-022-05489-0
person Authors
Krumm, B.E., Zhang, S., Gumpper, R.H., Liu, Y., Fay, J.F., Huang, X.P., Roth, B.L., Cao, C.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Krumm, B.E., Zhang, S., Gumpper, R.H., Liu, Y., Fay, J.F., Huang, X.P., Roth, B.L., Cao, C. , provided free of copyright via the Protein DataBank. View original data or read license terms.
