PDB | 8aw2 Mouse serotonin 5-HT3A receptor
Mouse serotonin 5-HT3A receptor in complex with vortioxetine
label Keywords
pentameric ligand-gated ion channel, serotonin receptor, vortioxetine, membrane protein
event_note Published
10/16/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Vortioxetine
Original publication
import_contacts Title
Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors.
import_contacts Journal
Nat.Struct.Mol.Biol. 2024
import_contacts DOI
10.1038/s41594-024-01282-x
person Authors
Schoehn, G., Juillan-Binard, C., Nury, H., Brun, C.C., Kristensen, A.S., Lyngby, S.M., Baud, D., Pedersen, A.J., Lopez-Sanchez, U., Bang-Andersen, B., Lummis, S.C.R., Munro, L.J., Pedersen, M.G., Neyton, J., Chipot, C., Schiott, B., Ladefoged, L.K., Dehez, F.
copyrightData provided by Research Collaboration for Structural Biology, Schoehn, G., Juillan-Binard, C., Nury, H., Brun, C.C., Kristensen, A.S., Lyngby, S.M., Baud, D., Pedersen, A.J., Lopez-Sanchez, U., Bang-Andersen, B., Lummis, S.C.R., Munro, L.J., Pedersen, M.G., Neyton, J., Chipot, C., Schiott, B., Ladefoged, L.K., Dehez, F. , provided free of copyright via the Protein DataBank. View original data or read license terms.
