PDB | 7yj2 SPT-ORMDL3 (ORMDL3-N13A) complex

Cryo-EM structure of SPT-ORMDL3 (ORMDL3-N13A) complex

label Keywords
ceramide, transferase-inhibitor complex
event_note Published
06/25/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
PYRIDOXAL-5'-PHOSPHATE

Original publication

import_contacts Title
Ceramide sensing by human SPT-ORMDL complex for establishing sphingolipid homeostasis.
import_contacts Journal
Nat Commun 2023
import_contacts DOI
10.1038/s41467-023-39274-y
person Authors
Fang, Q., Mahawar, U., Dong, F., Wu, X., Zhang, Z., Liu, P., Gong, X., Xie, T., Yue, J., Wattenberg, B.W., Vohra, H., Farooq, F., Liu, W.

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