PDB | 7xnl Human KCNQ1-CaM-ML277-PIP2 complex in state A
human KCNQ1-CaM-ML277-PIP2 complex in state A
label Keywords
potassium voltage-gated channel, ml277, pip2, membrane protein
event_note Published
07/03/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
POTASSIUM ION, (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylbenzene-1-sulfonyl)piperidine-2-carboxamide, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Original publication
import_contacts Title
Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers.
import_contacts Journal
Proc.Natl.Acad.Sci.USA 2022
import_contacts DOI
10.1073/pnas.2207067119
person Authors
Guo, J., Huang, Y., Zhong, L., Hou, P., Zhang, Y., Yang, W., Ma, D., Lai, D., Ye, F., Yan, Z., Yao, J.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Guo, J., Huang, Y., Zhong, L., Hou, P., Zhang, Y., Yang, W., Ma, D., Lai, D., Ye, F., Yan, Z., Yao, J. , provided free of copyright via the Protein DataBank. View original data or read license terms.
