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      PDB | 7wys Crystal structures of Na+,K+-ATPase

      Crystal structures of Na+,K+-ATPase in complex with istaroxime

      label Keywords
      na+, k+-atpase, membrane protein, ion transport, cardiotonic steroids
      event_note Published
      02/16/2022
      blur_on Resolution
      3.71 Å
      filter_center_focus Method
      X-RAY DIFFRACTION
      add_circle Ligands
      MAGNESIUM ION, SODIUM ION, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, (3E,5S,8R,9S,10R,13S,14S)-3-(2-azanylethoxyimino)-10,13-dimethyl-1,2,4,5,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-6,17-dione, CHOLESTEROL, 2-acetamido-2-deoxy-beta-D-glucopyranose

      Original publication

      import_contacts Title
      Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
      import_contacts Journal
      Proc.Natl.Acad.Sci.USA 2022
      import_contacts DOI
      10.1073/pnas.2123226119
      person Authors
      Cornelius, F., Vilsen, B., Kanai, R., Toyoshima, C.

      Read article from Proc.Natl.Acad.Sci.USA

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Cornelius, F., Vilsen, B., Kanai, R., Toyoshima, C. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

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