PDB | 7wld Human glycosylphosphatidylinositol transamidase complex at 2.53 Angstrom resolution
Cryo-EM structure of the human glycosylphosphatidylinositol transamidase complex at 2.53 Angstrom resolution
label Keywords
gpi anchoring, gpi-ap, glycosylphosphatidylinositol transamidase, gpi transamidase, membrane protein complex, transferase
event_note Published
01/13/2022
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
CHOLESTEROL HEMISUCCINATE, Digitonin, (4S,7R)-7-[(hexadecanoyloxy)methyl]-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-3,5,8-trioxa-4lambda~5~-phosphahexacosan-1-aminium, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CALCIUM ION, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, 2-azanylethyl [(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-2,4,5-tris(oxidanyl)oxan-3-yl] hydrogen phosphate, 2-amino-2-deoxy-alpha-D-glucopyranose, CARDIOLIPIN, [(2R)-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] octadecanoate, [(2~{R})-1-hexadecanoyloxy-3-[[(1~{S},2~{R},3~{R},4~{S},5~{S},6~{R})-2-hexadecanoyloxy-3,4,5,6-tetrakis(oxidanyl)cyclohexyl]oxy-oxidanyl-phosphoryl]oxy-propan-2-yl] (9~{Z},11~{Z})-octadeca-9,11-dienoate
Original publication
import_contacts Title
Molecular insights into biogenesis of glycosylphosphatidylinositol anchor proteins.
import_contacts Journal
Nat Commun 2022
import_contacts DOI
10.1038/s41467-022-30250-6
person Authors
Bao, J., Chao, Y., Zhou, Z., Luo, Y., Li, T., Qu, Q., Xu, Y., Jia, G., Li, D., Su, Z.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Bao, J., Chao, Y., Zhou, Z., Luo, Y., Li, T., Qu, Q., Xu, Y., Jia, G., Li, D., Su, Z. , provided free of copyright via the Protein DataBank. View original data or read license terms.
