PDB | 7wf4 Composite map of human Kv1.3 channel in dalazatide-bound state

Composite map of human Kv1.3 channel in dalazatide-bound state with beta subunits

label Keywords
ion channel, kv channel, potassium channel, peptide toxin, shk, dalazatide, selectivity filter, molecular dynamics simulation, membrane protein
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION

Original publication

import_contacts Title
Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug.
import_contacts Journal
Proc.Natl.Acad.Sci.USA 2022
import_contacts DOI
10.1073/pnas.2113536119
person Authors
Chandy, K.G., Tyagi, A., Bhushan, S., Goay, S.S.M., Ong, S.T., Vorobyov, I., Bajaj, S., Zhao, Y., Ahmed, T., Jian, S., Tian, C.

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