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      PDB | 7wdb Human TRPC5 channel

      Human TRPC5 channel in complex with riluzole

      label Keywords
      trpc5, riluzole, activator, membrane protein
      event_note Published
      03/26/2025
      filter_center_focus Method
      ELECTRON MICROSCOPY
      add_circle Ligands
      (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL HEMISUCCINATE, ZINC ION, CALCIUM ION, 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine, PHOSPHATIDYLETHANOLAMINE, [(2S)-1-oxidanyl-3-[(E)-tetradec-9-enoyl]oxy-propan-2-yl] (Z)-pentadec-9-enoate

      Original publication

      import_contacts Title
      Structural identification of riluzole-binding site on human TRPC5.
      import_contacts Journal
      Cell Discov 2022
      import_contacts DOI
      10.1038/s41421-022-00410-5
      person Authors
      Chen, L., Yang, Y., Wei, M.

      Read article from Cell Discov

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Chen, L., Yang, Y., Wei, M. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

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