PDB | 7wc9 Serotonin 2A receptor

Crystal structure of serotonin 2A receptor in complex with non-hallucinogenic psychedelic analog

label Keywords
serotonin 2a receptor, non-hallucinogenic psychedelic, membrane protein, serotonin, 5-ht
event_note Published
11/06/2024
blur_on Resolution
2.5 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
MAGNESIUM ION, CHOLESTEROL, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (10~{R},15~{S})-12-[3-(2-methoxyphenyl)propyl]-4-methyl-1,4,12-triazatetracyclo[7.6.1.0^{5,16}.0^{10,15}]hexadeca-5(16),6,8-triene, PENTAETHYLENE GLYCOL, DI(HYDROXYETHYL)ETHER

Original publication

import_contacts Title
Structure-based discovery of nonhallucinogenic psychedelic analogs.
import_contacts Journal
Science 2022
import_contacts DOI
10.1126/science.abl8615
person Authors
Qi, J., Chen, Z., Cheng, J., Tang, L., Wang, H., Yu, J., Luo, Z., Li, J., He, L., Cao, D., Wang, S., Fan, L., Liu, X.

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