PDB | 7wc8 Serotonin 2A receptor
Crystal structure of serotonin 2A receptor in complex with lumateperone
label Keywords
serotonin 2a receptor, serotonin, 5-ht, membrane protein, lumateperone
event_note Published
11/13/2024
blur_on Resolution
2.45 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
MAGNESIUM ION, CHOLESTEROL, PENTAETHYLENE GLYCOL, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-(4-fluorophenyl)-4-[(10~{R},15~{S})-4-methyl-1,4,12-triazatetracyclo[7.6.1.0^{5,16}.0^{10,15}]hexadeca-5,7,9(16)-trien-12-yl]butan-1-one, DI(HYDROXYETHYL)ETHER
Original publication
import_contacts Title
Structure-based discovery of nonhallucinogenic psychedelic analogs.
import_contacts Journal
Science 2022
import_contacts DOI
10.1126/science.abl8615
person Authors
Qi, J., Chen, Z., Cheng, J., Tang, L., Wang, H., Yu, J., Luo, Z., Li, J., He, L., Cao, D., Wang, S., Fan, L., Liu, X.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Qi, J., Chen, Z., Cheng, J., Tang, L., Wang, H., Yu, J., Luo, Z., Li, J., He, L., Cao, D., Wang, S., Fan, L., Liu, X. , provided free of copyright via the Protein DataBank. View original data or read license terms.
