PDB | 7w7f Human NaV1.3/beta1/beta2-ICA121431
Cryo-EM structure of human NaV1.3/beta1/beta2-ICA121431
label Keywords
ion channel, drug, antagonist, membrane protein
event_note Published
07/02/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate, 2,2-diphenyl-~{N}-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]ethanamide, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en
Original publication
import_contacts Title
Structural basis for modulation of human Na V 1.3 by clinical drug and selective antagonist.
import_contacts Journal
Nat Commun 2022
import_contacts DOI
10.1038/s41467-022-28808-5
person Authors
Zheng, Y., Gao, Y., Sun, J., Xu, F., Jiang, D., Zhang, H., Zhao, Y., Zhang, X.C., Xu, H., Li, X., Yang, B., Zhang, S., Dong, Y.
copyrightData provided by Research Collaboration for Structural Biology, Zheng, Y., Gao, Y., Sun, J., Xu, F., Jiang, D., Zhang, H., Zhao, Y., Zhang, X.C., Xu, H., Li, X., Yang, B., Zhang, S., Dong, Y. , provided free of copyright via the Protein DataBank. View original data or read license terms.
