PDB | 7w49 Gastric proton pump complexed
Crystal structure of the gastric proton pump complexed with soraprazan
label Keywords
cation pump, p-type atpase, gastric, proton pump, membrane protein, p-cab, hydrolase
event_note Published
11/13/2024
blur_on Resolution
3.1 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
MAGNESIUM ION, RUBIDIUM ION, Soraprazan, 2-acetamido-2-deoxy-beta-D-glucopyranose
Original publication
import_contacts Title
Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump.
import_contacts Journal
J.Med.Chem. 2022
import_contacts DOI
10.1021/acs.jmedchem.2c00338
person Authors
Abe, K., Oshima, A., Madapally, H.V., Hayashida, K., Morita, M., Gerle, C., Shigematsu, H., Khandelia, H., Tanaka, S., Yamagishi, T.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Abe, K., Oshima, A., Madapally, H.V., Hayashida, K., Morita, M., Gerle, C., Shigematsu, H., Khandelia, H., Tanaka, S., Yamagishi, T. , provided free of copyright via the Protein DataBank. View original data or read license terms.
