PDB | 7vug Class A orphan GPCR
Cryo-EM structure of a class A orphan GPCR in complex with Gi
label Keywords
orphan g protein coupled-receptor, membrane protein
event_note Published
06/18/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
3-chloranyl-N-[2-oxidanylidene-2-[[(1S)-1-phenylethyl]amino]ethyl]benzamide
Original publication
import_contacts Title
Molecular insights into ligand recognition and G protein coupling of the neuromodulatory orphan receptor GPR139.
import_contacts Journal
Cell Res. 2022
import_contacts DOI
10.1038/s41422-021-00591-w
person Authors
Harpsoe, K., Wu, M., Chen, N., Larionova, M., Trapkov, B., Liu, J., Liu, K., Gentry, P.R., Hua, T., Zhou, Y., Liu, Z.J., Gloriam, D.E., Wu, L., Daver, H., Brauner-Osborne, H.
copyrightData provided by Research Collaboration for Structural Biology, Harpsoe, K., Wu, M., Chen, N., Larionova, M., Trapkov, B., Liu, J., Liu, K., Gentry, P.R., Hua, T., Zhou, Y., Liu, Z.J., Gloriam, D.E., Wu, L., Daver, H., Brauner-Osborne, H. , provided free of copyright via the Protein DataBank. View original data or read license terms.
