PDB | 7vnp Structure of human KCNQ4-ML213 complex

Structure of human KCNQ4-ML213 complex with PIP2

label Keywords
kcnq4, ml213, pip2, cryo-em, membrane protein
event_note Published
06/19/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
[(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate, POTASSIUM ION, (1S,2S,4R)-N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamid

Original publication

import_contacts Title
Structural insights into the lipid and ligand regulation of a human neuronal KCNQ channel.
import_contacts Journal
Neuron 2022
import_contacts DOI
10.1016/j.neuron.2021.10.029
person Authors
Zheng, Y., Wang, F., Shu, Y., Dong, S., Liu, H., Xu, F., Li, G.L., Wang, S., Chen, Y.

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