PDB | 7vfv Human N-type voltage gated calcium channel CaV2.2-alpha2/delta1-beta1 complex, bound to PD173212

Human N-type voltage gated calcium channel CaV2.2-alpha2/delta1-beta1 complex, bound to PD173212

label Keywords
voltage gated calcium channel, n-type, complex, membrane protein
event_note Published
09/13/2021
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
HEXADECANE, CHOLESTEROL HEMISUCCINATE, [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate, (2~{S})-~{N}-[(2~{S})-1-(~{tert}-butylamino)-1-oxidanylidene-3-(4-phenylmethoxyphenyl)propan-2-yl]-2-[(4-~{tert}-butylphenyl)methyl-methyl-amino]-4-methyl-pentanamide, CALCIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose

Original publication

import_contacts Title
Closed-state inactivation and pore-blocker modulation mechanisms of human Ca V 2.2.
import_contacts Journal
Cell Rep 2021
import_contacts DOI
10.1016/j.celrep.2021.109931
person Authors
Yuan, T., Gao, Y., Li, Y., Xu, S., Wang, Y., Li, B., Jiang, D., Huang, Z., Zhao, Y., Zhang, X.C., Yang, B., Yu, Z., Dong, Y.

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