PDB | 7v6y Patched in lipid nanodisc - the wildtype, 3.5 angstrom (re-processed
Cryo-EM structure of Patched in lipid nanodisc - the wildtype, 3.5 angstrom (re-processed with dataset of 7dzq)
label Keywords
caveolae, hedgehog signaling, lipid nanodisc, patched, ptc1 dimer, membrane protein
event_note Published
03/19/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
CHOLESTEROL, (2S)-2-azanyl-3-[[(2S)-3-butanoyloxy-2-dec-9-enoyloxy-propoxy]-oxidanyl-phosphoryl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose
Original publication
import_contacts Title
Cryo-EM study of patched in lipid nanodisc suggests a structural basis for its clustering in caveolae.
import_contacts Journal
Structure 2021
import_contacts DOI
10.1016/j.str.2021.06.004
person Authors
Zhou, X., Zhang, X., Wang, Q., Luo, Y., Ma, L., Li, D., Zhao, Y., Cai, H., Qu, Q., Fan, J., Wu, H., Cong, Y., Wan, G.
copyrightData provided by Research Collaboration for Structural Biology, Zhou, X., Zhang, X., Wang, Q., Luo, Y., Ma, L., Li, D., Zhao, Y., Cai, H., Qu, Q., Fan, J., Wu, H., Cong, Y., Wan, G. , provided free of copyright via the Protein DataBank. View original data or read license terms.