PDB | 7v6y Patched in lipid nanodisc - the wildtype, 3.5 angstrom (re-processed

Cryo-EM structure of Patched in lipid nanodisc - the wildtype, 3.5 angstrom (re-processed with dataset of 7dzq)

label Keywords
caveolae, hedgehog signaling, lipid nanodisc, patched, ptc1 dimer, membrane protein
event_note Published
03/19/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
CHOLESTEROL, (2S)-2-azanyl-3-[[(2S)-3-butanoyloxy-2-dec-9-enoyloxy-propoxy]-oxidanyl-phosphoryl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose

Original publication

import_contacts Title
Cryo-EM study of patched in lipid nanodisc suggests a structural basis for its clustering in caveolae.
import_contacts Journal
Structure 2021
import_contacts DOI
10.1016/j.str.2021.06.004
person Authors
Zhou, X., Zhang, X., Wang, Q., Luo, Y., Ma, L., Li, D., Zhao, Y., Cai, H., Qu, Q., Fan, J., Wu, H., Cong, Y., Wan, G.

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