PDB | 7v68 An Agonist and PAM-bound Class A GPCR
An Agonist and PAM-bound Class A GPCR with Gi protein complex structure
label Keywords
m4r-gi complex, membrane protein
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium, 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide
Original publication
import_contacts Title
The unconventional activation of the muscarinic acetylcholine receptor M4R by diverse ligands.
import_contacts Journal
Nat Commun 2022
import_contacts DOI
10.1038/s41467-022-30595-y
person Authors
Chen, Z., Wang, J., Liu, S., Chen, N., Xu, Y., Li, F., Liu, J., Wang, H., Cheng, J., Hua, T., Zhao, S., Cao, D., Wu, L., Wang, S., Wu, M., Wang, T.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Chen, Z., Wang, J., Liu, S., Chen, N., Xu, Y., Li, F., Liu, J., Wang, H., Cheng, J., Hua, T., Zhao, S., Cao, D., Wu, L., Wang, S., Wu, M., Wang, T. , provided free of copyright via the Protein DataBank. View original data or read license terms.
