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PDB | 7tuy GSK682753A-bound EBI2/GPR183

Cryo-EM structure of GSK682753A-bound EBI2/GPR183

label Keywords
ebi2, gpr183, oxysterol, gpcr, signaling, immunity, immunocyte migration, immune system
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
8-[(2E)-3-(4-chlorophenyl)prop-2-enoyl]-3-[(3,4-dichlorophenyl)methyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one

Original publication

import_contacts Title
Structures of oxysterol sensor EBI2/GPR183, a key regulator of the immune response.
import_contacts Journal
Structure 2022
import_contacts DOI
10.1016/j.str.2022.04.006
person Authors
Huang, W., Chen, H., Li, X.

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