PDB | 7tj8 Human Nax channel
Cryo-EM structure of the human Nax channel in complex with beta3 solved in nanodiscs
label Keywords
sodium channel, nav, ion channel, metal transport
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PALMITIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL
Original publication
import_contacts Title
Structure-guided unlocking of Na X reveals a non-selective tetrodotoxin-sensitive cation channel.
import_contacts Journal
Nat Commun 2022
import_contacts DOI
10.1038/s41467-022-28984-4
person Authors
Chang, T., Tang, J., Pless, S.A., Chua, H.C., Payandeh, J., Noland, C.L., Braun, N., Kschonsak, M., Heusser, S.A., Ciferri, C., Tam, C., Arthur, C.P.
copyrightData provided by Research Collaboration for Structural Biology, Chang, T., Tang, J., Pless, S.A., Chua, H.C., Payandeh, J., Noland, C.L., Braun, N., Kschonsak, M., Heusser, S.A., Ciferri, C., Tam, C., Arthur, C.P. , provided free of copyright via the Protein DataBank. View original data or read license terms.
