PDB | 7tao Bafilomycin A1 bound to yeast VO V-ATPase
Cryo-EM structure of bafilomycin A1 bound to yeast VO V-ATPase
label Keywords
inhibitor, complex, proton pump, atpase, membrane protein
event_note Published
10/30/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(5R)-2,4-dideoxy-1-C-{(2S,3R,4S)-3-hydroxy-4-[(2R,3S,4E,6E,9R,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxo-1-oxacyclohexadeca-4,6,12,14-tetraen-2-yl]pentan-2-yl}-4-methyl-5-propan-2-yl-alpha-D-threo-pentopyranose
Original publication
import_contacts Title
Cryo-EM of the Yeast V O Complex Reveals Distinct Binding Sites for Macrolide V-ATPase Inhibitors.
import_contacts Journal
Acs Chem.Biol. 2022
import_contacts DOI
10.1021/acschembio.1c00894
person Authors
Muller, R., Benlekbir, S., Rubinstein, J.L., Kirsch, S.H., Keon, K.A.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Muller, R., Benlekbir, S., Rubinstein, J.L., Kirsch, S.H., Keon, K.A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
