PDB | 7sv7 The complex of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR)
The complex of phosphorylated human cystic fibrosis transmembrane conductance regulator (CFTR) with ATP/Mg and Tezacaftor (VX-661)
label Keywords
abc transporter, ion channel, folding correction, atp-binding protein, membrane protein
event_note Published
05/21/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, nonane, DODECANE, CHOLESTEROL, TETRADECANE, heptadecane, Tezacaftor
Original publication
import_contacts Title
Mechanism of CFTR correction by type I folding correctors.
import_contacts Journal
Cell 2022
import_contacts DOI
10.1016/j.cell.2021.12.009
person Authors
Chen, J., Fiedorczuk, K.
copyrightData provided by Research Collaboration for Structural Biology, Chen, J., Fiedorczuk, K. , provided free of copyright via the Protein DataBank. View original data or read license terms.
