PDB | 7shf GPR158 coupled to the RGS7-Gbeta5 complex
Cryo-EM structure of GPR158 coupled to the RGS7-Gbeta5 complex
label Keywords
receptor, complex, signaling protein
event_note Published
10/08/2021
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
CHOLESTEROL, (2S)-1-{[(S)-hydroxy{[(1s,2R,3R,4R,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5E,8E,11E,14E)-icosa-5,8,11,14-tetraenoate, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine
Original publication
import_contacts Title
Cryo-EM structure of human GPR158 receptor coupled to the RGS7-G beta 5 signaling complex.
import_contacts Journal
Science 2022
import_contacts DOI
10.1126/science.abl4732
person Authors
Strutzenberg, T.S., Laboute, T., Patil, D.N., Izard, T., Singh, A.K., Wu, D., Novick, S.J., Griffin, P.R., Robinson, C.V., Singh, S., Martemyanov, K.A., Hunt, J.F., Qiu, X.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Strutzenberg, T.S., Laboute, T., Patil, D.N., Izard, T., Singh, A.K., Wu, D., Novick, S.J., Griffin, P.R., Robinson, C.V., Singh, S., Martemyanov, K.A., Hunt, J.F., Qiu, X. , provided free of copyright via the Protein DataBank. View original data or read license terms.