PDB | 7shf GPR158 coupled to the RGS7-Gbeta5 complex

Cryo-EM structure of GPR158 coupled to the RGS7-Gbeta5 complex

label Keywords
receptor, complex, signaling protein
event_note Published
10/08/2021
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
CHOLESTEROL, (2S)-1-{[(S)-hydroxy{[(1s,2R,3R,4R,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5E,8E,11E,14E)-icosa-5,8,11,14-tetraenoate, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine

Original publication

import_contacts Title
Cryo-EM structure of human GPR158 receptor coupled to the RGS7-G beta 5 signaling complex.
import_contacts Journal
Science 2022
import_contacts DOI
10.1126/science.abl4732
person Authors
Strutzenberg, T.S., Laboute, T., Patil, D.N., Izard, T., Singh, A.K., Wu, D., Novick, S.J., Griffin, P.R., Robinson, C.V., Singh, S., Martemyanov, K.A., Hunt, J.F., Qiu, X.

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