PDB | 7sf7 LPHN3 (ADGRL3) 7TM domain bound to tethered agonist

LPHN3 (ADGRL3) 7TM domain bound to tethered agonist in complex with G protein heterotrimer

label Keywords
adhesion gpcr, lphn3, latrophilin, adgrl3, tethered agonist, stalk, stachel, minig13, g13 heterotrimer, g protein, cryoem, membrane protein
event_note Published
10/09/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands

Original publication

import_contacts Title
The tethered peptide activation mechanism of adhesion GPCRs.
import_contacts Journal
Nature 2022
import_contacts DOI
10.1038/s41586-022-04575-7
person Authors
Skiniotis, G., Peroto, M.C., Yardeni, E.H., Seven, A.B., Shalev-Benami, M., Tall, G.G., Vizurraga, A., Matzov, D., Su, H., Barros-Alvarez, X., Meyerowitz, J.G., Robertson, M.J., He, F., Papasergi-Scott, M.M., Panova, O., Kwarcinski, F.E., Nwokonko, R.M.

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