PDB | 7s8l Gq-coupled MRGPRX2

CryoEM structure of Gq-coupled MRGPRX2 with peptide agonist Cortistatin-14

label Keywords
gpcr, signaling protein
event_note Published
10/23/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands

Original publication

import_contacts Title
Structure, function and pharmacology of human itch GPCRs.
import_contacts Journal
Nature 2021
import_contacts DOI
10.1038/s41586-021-04126-6
person Authors
Abraham, S.N., Ye, W., Zhang, S., Roth, B.L., Cao, C., Krumm, B.E., Liu, J., English, J.G., Kang, H.J., Jin, J., Chen, H., Kroeze, W.K., Kim, K., Zhang, C., Jan, L.Y., Liu, Y., McCorvy, J.D., Hayes, B.W., Lansu, K., Huang, X.P., Singh, I., Bender, B.J., Shoichet, B.K., Karpiak, J., Gumpper, R.H., Slocum, S.T., Fay, J.F., DiBerto, J.F., Olsen, R.H.J.

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