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      PDB | 7s8b Cryo-EM structure of human TRPV6 in complex with channel blocker ruthenium red

      Cryo-EM structure of human TRPV6 in complex with channel blocker ruthenium red

      label Keywords
      transient receptor potential v family member 6, trp, channel, ruthenium red, channel blocker, antagonist, cnw11, nanodiscs, trpv6, membrane protein
      event_note Published
      06/05/2024
      filter_center_focus Method
      ELECTRON MICROSCOPY
      add_circle Ligands
      CHOLESTEROL HEMISUCCINATE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2)

      Original publication

      import_contacts Title
      Structural mechanisms of TRPV6 inhibition by ruthenium red and econazole.
      import_contacts Journal
      Nat Commun 2021
      import_contacts DOI
      10.1038/s41467-021-26608-x
      person Authors
      Nadezhdin, K.D., Neuberger, A., Sobolevsky, A.I.

      Read article from Nat Commun

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Nadezhdin, K.D., Neuberger, A., Sobolevsky, A.I. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

      play_circle_outline7s8b_default_dppc

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