PDB | 7rya S. Cerevisiae Cyp51 I471T Mutant Complexed
S. CEREVISIAE CYP51 I471T MUTANT COMPLEXED WITH ITRACONAZOLE
label Keywords
cyp51, oxidoreductase-oxidoreductase inhibitor complex, sterol biosynthesis, oxidoreductase
event_note Published
08/24/2021
blur_on Resolution
2.1 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
PROTOPORPHYRIN IX CONTAINING FE, 2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one
Original publication
import_contacts Title
Structural Insights into the Azole Resistance of the Candida albicans Darlington Strain Using Saccharomyces cerevisiae Lanosterol 14 alpha-Demethylase as a Surrogate.
import_contacts Journal
J Fungi (Basel) 2021
import_contacts DOI
10.3390/jof7110897
person Authors
Graham, D.O., Keniya, M.V., Wilson, R.K., Monk, B.C., Ruma, Y.N., Tyndall, J.D.A.
copyrightData provided by Research Collaboration for Structural Biology, Graham, D.O., Keniya, M.V., Wilson, R.K., Monk, B.C., Ruma, Y.N., Tyndall, J.D.A. , provided free of copyright via the Protein DataBank. View original data or read license terms.
