PDB | 7rmi SP6-11 biased agonist bound to active human neurokinin 1 receptor
SP6-11 biased agonist bound to active human neurokinin 1 receptor in complex with miniGs/q70
label Keywords
substance p, g protein, gpcr, neurokinin, tachykinin, signaling protein, signaling protein-membrane protein complex
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
Original publication
import_contacts Title
Selective G protein signaling driven by substance P-neurokinin receptor dynamics.
import_contacts Journal
Nat.Chem.Biol. 2022
import_contacts DOI
10.1038/s41589-021-00890-8
person Authors
Gondin, A.B., Veldhuis, N.A., Dror, R.O., Cheng, Y., Damgen, M.A., Manglik, A., Harris, J.A., Faust, B., Thal, D.M., Suomivuori, C.M.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Gondin, A.B., Veldhuis, N.A., Dror, R.O., Cheng, Y., Damgen, M.A., Manglik, A., Harris, J.A., Faust, B., Thal, D.M., Suomivuori, C.M. , provided free of copyright via the Protein DataBank. View original data or read license terms.
