PDB | 7rh6 Mycobacterial CIII2CIV2 supercomplex, inhibitor free, -Lpqe cyt cc open

Mycobacterial CIII2CIV2 supercomplex, inhibitor free, -Lpqe cyt cc open

label Keywords
electron transport chain, ciii2civ2 supercomplex, membrane protein
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
HEME C, (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, MENAQUINONE-9, COPPER (II) ION, HEME-A, CARDIOLIPIN, FE2/S2 (INORGANIC) CLUSTER, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, PROTOPORPHYRIN IX CONTAINING FE, PALMITIC ACID, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate

Original publication

import_contacts Title
Structure of mycobacterial CIII 2 CIV 2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203).
import_contacts Journal
Elife 2021
import_contacts DOI
10.7554/eLife.71959
person Authors
Imming, P., Brzezinski, P., Krol, S., Rubinstein, J.L., Abdelaziz, R., Yanofsky, D.J., Di Trani, J.M., Bueler, S.A.

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