PDB | 7qnb Human full-length beta3gamma2 GABA(A)R

Cryo-EM structure of human full-length beta3gamma2 GABA(A)R in complex with GABA and nanobody Nb25

label Keywords
pentameric ligand-gated ion channel, neurotransmitter receptor, gaba receptor, membrane protein
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID

Original publication

import_contacts Title
Differential assembly diversifies GABA A receptor structures and signalling.
import_contacts Journal
Nature 2022
import_contacts DOI
10.1038/s41586-022-04517-3
person Authors
Zhou, X., Malinauskas, T., Masiulis, S., Chirgadze, D.Y., Hardwick, S.W., Miller, K.W., Aricescu, A.R., Jounaidi, Y., Naydenova, K., Miehling, J., Sente, A., Desai, R.

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