PDB | 7qn7 Human full-length extrasynaptic alpha4beta3delta GABA(A)R
Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with GABA, histamine and nanobody Nb25
label Keywords
pentameric ligand-gated ion channel, neurotransmitter receptor, gaba receptor, membrane protein
event_note Published
11/13/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, DECANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, HEXADECANE, HISTAMINE
Original publication
import_contacts Title
Differential assembly diversifies GABA A receptor structures and signalling.
import_contacts Journal
Nature 2022
import_contacts DOI
10.1038/s41586-022-04517-3
person Authors
Zhou, X., Malinauskas, T., Masiulis, S., Chirgadze, D.Y., Hardwick, S.W., Miller, K.W., Aricescu, A.R., Jounaidi, Y., Naydenova, K., Miehling, J., Sente, A., Desai, R.
copyrightData provided by Research Collaboration for Structural Biology, Zhou, X., Malinauskas, T., Masiulis, S., Chirgadze, D.Y., Hardwick, S.W., Miller, K.W., Aricescu, A.R., Jounaidi, Y., Naydenova, K., Miehling, J., Sente, A., Desai, R. , provided free of copyright via the Protein DataBank. View original data or read license terms.
