PDB | 7q0m Peptide transporter YePEPT-K314A

Crystal structure of the peptide transporter YePEPT-K314A in complex with LZNV at 2.66 A

label Keywords
membrane protein, mfs, peptide transporter, solute transporter, inhibitor bound, lznv, pept1
event_note Published
02/07/2024
blur_on Resolution
2.54 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
(2~{S})-2-[[(2~{S})-2-azanyl-6-[(4-nitrophenyl)methoxycarbonylamino]hexanoyl]amino]-3-methyl-butanoic acid, UNDECYL-MALTOSIDE

Original publication

import_contacts Title
Peptide transporter structure reveals binding and action mechanism of a potent PEPT1 and PEPT2 inhibitor.
import_contacts Journal
Commun Chem 2022
import_contacts DOI
10.1038/s42004-022-00636-0
person Authors
Jeckelmann, J.M., Fotiadis, D., Ucurum, Z., Boggavarapu, R., Ilgu, H., Stauffer, M.

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