PDB | 7pxh Emodepside-bound Drosophila Slo channel
Emodepside-bound Drosophila Slo channel
label Keywords
potassium transport, bk channel, transport protein
event_note Published
10/08/2021
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
CALCIUM ION, MAGNESIUM ION, (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CHOLESTEROL, POTASSIUM ION, (3~{S},6~{R},9~{S},12~{R},15~{S},18~{R},21~{S},24~{R})-4,6,10,16,18,22-hexamethyl-3,9,15,21-tetrakis(2-methylpropyl)-12,24-bis[(4-morpholin-4-ylphenyl)methyl]-1,7,13,19-tetraoxa-4,10,16,22-tetrazacyclotetracosane-2,5,8,11,14,17,20,23-octone
Original publication
import_contacts Title
Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM.
import_contacts Journal
Nat Commun 2021
import_contacts DOI
10.1038/s41467-021-27435-w
person Authors
Ebbinghaus-Kintscher, U., Maertens, B., Brockmann, A., Hofnagel, O., Gutbrod, O., Raunser, S., Raisch, T., Freigang, J., Kubicek, J.
copyrightData provided by Research Collaboration for Structural Biology, Ebbinghaus-Kintscher, U., Maertens, B., Brockmann, A., Hofnagel, O., Gutbrod, O., Raunser, S., Raisch, T., Freigang, J., Kubicek, J. , provided free of copyright via the Protein DataBank. View original data or read license terms.