PDB | 7px4 Adenosine A2A receptor (A2A-PSB1-bRIL)
Crystal structure of the adenosine A2A receptor (A2A-PSB1-bRIL) in complex with preladenant conjugate PSB-2113
label Keywords
gpcr, membrane protein, a2a, g protein-coupled receptor, adenosine receptor, preladenant
event_note Published
11/13/2024
blur_on Resolution
2.25 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
CHOLESTEROL, Preladenant conjugate PSB-2113, OLEIC ACID, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER
Original publication
import_contacts Title
Single Stabilizing Point Mutation Enables High-Resolution Co-Crystal Structures of the Adenosine A 2A Receptor with Preladenant Conjugates.
import_contacts Journal
Angew.Chem.Int.Ed.Engl. 2022
import_contacts DOI
10.1002/anie.202115545
person Authors
Klapschinski, T.A., Schlegel, J.G., Claff, T., Muller, C.E., Vaassen, V.J., Voss, J.H., Labahn, J., Tiruttani Subhramanyam, U.K., Vielmuth, C.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Klapschinski, T.A., Schlegel, J.G., Claff, T., Muller, C.E., Vaassen, V.J., Voss, J.H., Labahn, J., Tiruttani Subhramanyam, U.K., Vielmuth, C. , provided free of copyright via the Protein DataBank. View original data or read license terms.
