PDB | 7p2l Thermostabilised 7TM domain of human mGlu5 receptor bound to photoswitchable ligand alloswitch-1
thermostabilised 7TM domain of human mGlu5 receptor bound to photoswitchable ligand alloswitch-1
label Keywords
g protein coupled receptor, mglu5 7tm, photoswitchable ligand, allosteric modulator, signaling protein
event_note Published
01/31/2024
blur_on Resolution
2.54 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
2-chloranyl-~{N}-[2-methoxy-4-[(~{E})-pyridin-2-yldiazenyl]phenyl]benzamide
Original publication
import_contacts Title
Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations.
import_contacts Journal
Cell Rep 2021
import_contacts DOI
10.1016/j.celrep.2021.109648
person Authors
Goudet, C., Llebaria, A., Hoh, F., Berto, L., Catena, J., Vinothkumar, K.R., Huang, C.Y., Font-Ingles, J., Gomez-Santacana, X., Quast, R.B., Nasrallah, C., Lebon, G., Pin, J.P., Berizzi, A.E., Baneres, J.L., Malhaire, F., Dumazer, A., Briot, J., Cannone, G., Kniazeff, J., Rottier, K.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Goudet, C., Llebaria, A., Hoh, F., Berto, L., Catena, J., Vinothkumar, K.R., Huang, C.Y., Font-Ingles, J., Gomez-Santacana, X., Quast, R.B., Nasrallah, C., Lebon, G., Pin, J.P., Berizzi, A.E., Baneres, J.L., Malhaire, F., Dumazer, A., Briot, J., Cannone, G., Kniazeff, J., Rottier, K. , provided free of copyright via the Protein DataBank. View original data or read license terms.
