PDB | 7ouk BDM88855 inhibitor bound to the transmembrane domain of AcrB
BDM88855 inhibitor bound to the transmembrane domain of AcrB
label Keywords
multidrug efflux pump, membrane protein, transport protein
event_note Published
01/31/2024
blur_on Resolution
2.6 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
DODECYL-BETA-D-MALTOSIDE, 3-chloranyl-2-piperazin-1-yl-quinoline, 1,2-ETHANEDIOL, N-OCTANE, TETRADECANE, GLYCEROL, DECANE, (2S)-3-hydroxypropane-1,2-diyl didecanoate, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, SULFATE ION, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate
Original publication
import_contacts Title
Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps.
import_contacts Journal
Nat Commun 2022
import_contacts DOI
10.1038/s41467-021-27726-2
person Authors
Vargiu, A.V., Herrmann, A., Herledan, A., Vieira Da Cruz, A., Tam, H.K., Kirchner, M.A., Flipo, M., Hartkoorn, R.C., Pradel, E., Willand, N., Malloci, G., Compagne, N., Ple, C., Pos, K.M., Deprez, B., Foong, W.E., Ballee, A., Jimenez-Castellanos, J.C., Muller, R.T., Moshfegh, P.
copyrightData provided by Research Collaboration for Structural Biology, Vargiu, A.V., Herrmann, A., Herledan, A., Vieira Da Cruz, A., Tam, H.K., Kirchner, M.A., Flipo, M., Hartkoorn, R.C., Pradel, E., Willand, N., Malloci, G., Compagne, N., Ple, C., Pos, K.M., Deprez, B., Foong, W.E., Ballee, A., Jimenez-Castellanos, J.C., Muller, R.T., Moshfegh, P. , provided free of copyright via the Protein DataBank. View original data or read license terms.
