PDB | 7oh7 Drs2p-Cdc50p in the E1-AMPPCP state
Cryo-EM structure of Drs2p-Cdc50p in the E1-AMPPCP state with PI4P bound
label Keywords
lipid flippase, p4 atpase, trans-golgi network, phosphatidylserine transport, membrane protein
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, MAGNESIUM ION
Original publication
import_contacts Title
Structural basis of substrate-independent phosphorylation in a P4-ATPase lipid flippase
import_contacts Journal
J.Mol.Biol. 2021
import_contacts DOI
10.1016/j.jmb.2021.167062
person Authors
Montigny, C., Lenoir, G., Boesen, T., Lyons, J.A., Dieudonne, T., Timcenko, M., Nissen, P.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Montigny, C., Lenoir, G., Boesen, T., Lyons, J.A., Dieudonne, T., Timcenko, M., Nissen, P. , provided free of copyright via the Protein DataBank. View original data or read license terms.
