PDB | 7nfd Structure of mitoxantrone-bound ABCG2
Structure of mitoxantrone-bound ABCG2
label Keywords
abcg2, mitoxantrone, substrate, abc transporter, anticancer drugs, cavity 1, cryo-em, membrane protein
event_note Published
07/09/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE
Original publication
import_contacts Title
Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2.
import_contacts Journal
J.Mol.Biol. 2021
import_contacts DOI
10.1016/j.jmb.2021.166980
person Authors
Locher, K.P., Jackson, S.M., Manolaridis, I., Ni, D., Kowal, J., Stahlberg, H.
copyrightData provided by Research Collaboration for Structural Biology, Locher, K.P., Jackson, S.M., Manolaridis, I., Ni, D., Kowal, J., Stahlberg, H. , provided free of copyright via the Protein DataBank. View original data or read license terms.
