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      PDB | 7nez Structure of topotecan-bound ABCG2

      Structure of topotecan-bound ABCG2

      label Keywords
      abcg2, topotecan, substrate, abc transporter, anticancer drugs, cavity 1, cryo-em, membrane protein
      event_note Published
      10/16/2024
      filter_center_focus Method
      ELECTRON MICROSCOPY
      add_circle Ligands
      (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, 2-acetamido-2-deoxy-beta-D-glucopyranose

      Original publication

      import_contacts Title
      Structural Basis of Drug Recognition by the Multidrug Transporter ABCG2.
      import_contacts Journal
      J.Mol.Biol. 2021
      import_contacts DOI
      10.1016/j.jmb.2021.166980
      person Authors
      Locher, K.P., Jackson, S.M., Manolaridis, I., Ni, D., Kowal, J., Stahlberg, H.

      Read article from J.Mol.Biol.

      Member of

      copyrightData provided by Research Collaboration for Structural Biology, Locher, K.P., Jackson, S.M., Manolaridis, I., Ni, D., Kowal, J., Stahlberg, H. , provided free of copyright via the Protein DataBank. View original data or read license terms.

      Simulations available

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