PDB | 7n4v Structure of cholesterol-bound human NPC1L1

Structure of cholesterol-bound human NPC1L1

label Keywords
transporter, membrane protein
event_note Published
10/30/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate

Original publication

import_contacts Title
Structures of dimeric human NPC1L1 provide insight into mechanisms for cholesterol absorption.
import_contacts Journal
Sci Adv 2021
import_contacts DOI
10.1126/sciadv.abh3997
person Authors
Liu, Y., Li, X., DeBose-Boyd, R.A., Long, T., Qin, Y.

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