PDB | 7mts MGlu2 - Gi Complex

CryoEM Structure of mGlu2 - Gi Complex

label Keywords
metabotropic glutamate receptor 2 (mglu2) (mglur2), family c g protein-coupled receptor (gpcr), heterotrimeric g protein, cryoem structure, membrane protein, membrane protein-signaling protein complex
event_note Published
10/30/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-methoxy-6-propyl-N-(2-{4-[(1H-tetrazol-5-yl)methoxy]phenyl}ethyl)thieno[2,3-d]pyrimidin-4-amine, GLUTAMIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose

Original publication

import_contacts Title
G-protein activation by a metabotropic glutamate receptor.
import_contacts Journal
Nature 2021
import_contacts DOI
10.1038/s41586-021-03680-3
person Authors
Schelshorn, D., Gao, Y., Mathiesen, J.M., Skiniotis, G., Zhang, C., Barros-Alvarez, X., Nwokonko, R.M., Meyerowitz, J.G., Robertson, M.J., de Lapeyriere, M., Papasergi-Scott, M.M., Rocher, J.P., Seven, A.B., Kobilka, B.K.

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