PDB | 7mfi Bovine sigma-2 receptor bound to cholesterol
Bovine sigma-2 receptor bound to cholesterol
label Keywords
receptor, sterol, dimer, membrane protein
event_note Published
04/09/2021
blur_on Resolution
2.81 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
CHOLESTEROL, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Original publication
import_contacts Title
Structures of the sigma 2 receptor enable docking for bioactive ligand discovery.
import_contacts Journal
Nature 2021
import_contacts DOI
10.1038/s41586-021-04175-x
person Authors
Moroz, Y.S., Shoichet, B.K., Lyu, J., Craik, V., Webb, C.M., Basbaum, A.I., Kruse, A.C., Liu, Y., Braz, J.M., Irwin, J.J., Tummino, T.A., Alon, A., Huang, X.P., Roth, B.L., O'Meara, M.J., Radchenko, D.S.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Moroz, Y.S., Shoichet, B.K., Lyu, J., Craik, V., Webb, C.M., Basbaum, A.I., Kruse, A.C., Liu, Y., Braz, J.M., Irwin, J.J., Tummino, T.A., Alon, A., Huang, X.P., Roth, B.L., O'Meara, M.J., Radchenko, D.S. , provided free of copyright via the Protein DataBank. View original data or read license terms.
