PDB | 7mdc Full-length wildtype ClbP inhibited by hexanoyl-D-asparagine boronic acid
Full-length wildtype ClbP inhibited by hexanoyl-D-asparagine boronic acid
label Keywords
colibactin peptidase, s12 peptidase, boronic acid inhibitor, hydrolase, hydrolase-hydrolase inhibitor complex
event_note Published
10/16/2024
blur_on Resolution
2.7 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
NONAETHYLENE GLYCOL, DIMETHYL SULFOXIDE, (2S)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, [(1S)-3-amino-1-(hexanoylamino)-3-oxopropyl]boronic acid, SULFATE ION, CHLORIDE ION
Original publication
import_contacts Title
A small molecule inhibitor prevents gut bacterial genotoxin production.
import_contacts Journal
Nat.Chem.Biol. 2023
import_contacts DOI
10.1038/s41589-022-01147-8
person Authors
Volpe, M.R., Balskus, E.P., Yao, J.J., Daniel-Ivad, M., Balbo, S., Villalta, P.W., Huang, H.C., Stornetta, A., Velilla, J.A., Bachovchin, D.A., Gaudet, R.
copyrightData provided by Research Collaboration for Structural Biology, Volpe, M.R., Balskus, E.P., Yao, J.J., Daniel-Ivad, M., Balbo, S., Villalta, P.W., Huang, H.C., Stornetta, A., Velilla, J.A., Bachovchin, D.A., Gaudet, R. , provided free of copyright via the Protein DataBank. View original data or read license terms.
