PDB | 7mbu Zebrafish TRPM5 E337A mutant in the presence of 5 mM calcium (high calcium occupancy in the transmembrane domain)
Cryo-EM structure of zebrafish TRPM5 E337A mutant in the presence of 5 mM calcium (high calcium occupancy in the transmembrane domain)
label Keywords
ion channel, trp channel, transport protein
event_note Published
05/28/2025
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, (25R)-14beta,17beta-spirost-5-en-3beta-ol
Original publication
import_contacts Title
Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition.
import_contacts Journal
Nat.Struct.Mol.Biol. 2021
import_contacts DOI
10.1038/s41594-021-00607-4
person Authors
Sabat, M., Orozco, I.J., Lu, W., Ruan, Z., Roth, R., Du, J., Haley, E., Myers, R.
copyrightData provided by Research Collaboration for Structural Biology, Sabat, M., Orozco, I.J., Lu, W., Ruan, Z., Roth, R., Du, J., Haley, E., Myers, R. , provided free of copyright via the Protein DataBank. View original data or read license terms.
