PDB | 7m95 Bovine sigma-2 receptor bound to Z1241145220
Bovine sigma-2 receptor bound to Z1241145220
label Keywords
receptor, sterol, dimer, membrane protein
event_note Published
03/30/2021
blur_on Resolution
2.41 Å
filter_center_focus Method
X-RAY DIFFRACTION
add_circle Ligands
3-[1-(3-phenylpropyl)-1,2,3,6-tetrahydropyridin-4-yl]-1H-pyrrolo[2,3-b]pyridine, CHOLESTEROL, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
Original publication
import_contacts Title
Structures of the sigma 2 receptor enable docking for bioactive ligand discovery.
import_contacts Journal
Nature 2021
import_contacts DOI
10.1038/s41586-021-04175-x
person Authors
Moroz, Y.S., Shoichet, B.K., Lyu, J., Craik, V., Webb, C.M., Basbaum, A.I., Kruse, A.C., Liu, Y., Braz, J.M., Irwin, J.J., Tummino, T.A., Alon, A., Huang, X.P., Roth, B.L., O'Meara, M.J., Radchenko, D.S.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Moroz, Y.S., Shoichet, B.K., Lyu, J., Craik, V., Webb, C.M., Basbaum, A.I., Kruse, A.C., Liu, Y., Braz, J.M., Irwin, J.J., Tummino, T.A., Alon, A., Huang, X.P., Roth, B.L., O'Meara, M.J., Radchenko, D.S. , provided free of copyright via the Protein DataBank. View original data or read license terms.
