PDB | 7m3g Asymmetric Activation of the Calcium Sensing Receptor Homodimer
Asymmetric Activation of the Calcium Sensing Receptor Homodimer
label Keywords
gpcr, calcium sensing receptor, active state, positive allosteric modulator, family c gpcr, membrane protein
event_note Published
11/20/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-[4-[(3S)-3-[[(1R)-1-naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]phenyl]ethanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, TRYPTOPHAN, CALCIUM ION, PHOSPHATE ION
Original publication
import_contacts Title
Asymmetric activation of the calcium-sensing receptor homodimer.
import_contacts Journal
Nature 2021
import_contacts DOI
10.1038/s41586-021-03691-0
person Authors
Rahman, S.N., Gao, Y., Mathiesen, J.M., Skiniotis, G., Zhang, C., Hannan, F.M., Meyerowitz, J.G., Robertson, M.J., Thakker, R.V., Panova, O., Brauner-Osborne, H., Seven, A.B.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Rahman, S.N., Gao, Y., Mathiesen, J.M., Skiniotis, G., Zhang, C., Hannan, F.M., Meyerowitz, J.G., Robertson, M.J., Thakker, R.V., Panova, O., Brauner-Osborne, H., Seven, A.B. , provided free of copyright via the Protein DataBank. View original data or read license terms.
