PDB | 7m3f Asymmetric Activation of the Calcium Sensing Receptor Homodimer

Asymmetric Activation of the Calcium Sensing Receptor Homodimer

label Keywords
gpcr, calcium sensing receptor, active state, positive allosteric modulator, family c gpcr, membrane protein
event_note Published
11/20/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
2-acetamido-2-deoxy-beta-D-glucopyranose, N-[(1R)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine, TRYPTOPHAN, CALCIUM ION, PHOSPHATE ION

Original publication

import_contacts Title
Asymmetric activation of the calcium-sensing receptor homodimer.
import_contacts Journal
Nature 2021
import_contacts DOI
10.1038/s41586-021-03691-0
person Authors
Rahman, S.N., Gao, Y., Mathiesen, J.M., Skiniotis, G., Zhang, C., Hannan, F.M., Meyerowitz, J.G., Robertson, M.J., Thakker, R.V., Panova, O., Brauner-Osborne, H., Seven, A.B.

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