PDB | 7ljc Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1
Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1 in complex with miniGs protein
label Keywords
dopamine receptor 2, gs protein, skf-81297, pam, ly3154207, signaling protein
event_note Published
11/20/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
(1R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, PALMITIC ACID
Original publication
import_contacts Title
Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
import_contacts Journal
Cell Res. 2021
import_contacts DOI
10.1038/s41422-021-00482-0
person Authors
Cheng, X., Wang, Y., Jiang, H., Zhang, C., Zhou, X.E., Zhuang, Y., Yi, W., Liu, Y., Zhang, H., Krumm, B., Roth, B.L., Zhang, Y., Xu, H.E., Huang, X.P., Jiang, Y.
Member of
copyrightData provided by Research Collaboration for Structural Biology, Cheng, X., Wang, Y., Jiang, H., Zhang, C., Zhou, X.E., Zhuang, Y., Yi, W., Liu, Y., Zhang, H., Krumm, B., Roth, B.L., Zhang, Y., Xu, H.E., Huang, X.P., Jiang, Y. , provided free of copyright via the Protein DataBank. View original data or read license terms.
