PDB | 7lep The composite LBD-TMD structure combined

The composite LBD-TMD structure combined from all hippocampal AMPAR subtypes at 3.25 Angstrom resolution

label Keywords
native hippocampal ion channel, membrane protein
event_note Published
11/06/2024
filter_center_focus Method
ELECTRON MICROSCOPY
add_circle Ligands
{[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, TETRADECANE, DECANE, 6-[2-chloro-6-(trifluoromethoxy)phenyl]-1H-benzimidazol-2-ol, N-OCTANE, DODECANE

Original publication

import_contacts Title
Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition.
import_contacts Journal
Nature 2021
import_contacts DOI
10.1038/s41586-021-03540-0
person Authors
Ha, T., Yu, J., Gouaux, E., Mitra, J., Clark, S., Rao, P.

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